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Human adipose-derived stem cell supernatant

Human Adipose Derived Stem Cell Conditioned Media


What is human stem cell supernatant?

Human stem cell culture supernatant is made by extracting stem cells present in the body and

This is the liquid (supernatant) that is produced during cultivation.

Stem cells have the ability to regenerate cells and tissues.

The culture medium contains many active ingredients, including cytokines (growth factors).

For this reason, it is currently attracting a great deal of attention in the beauty industry, regenerative medicine, and other fields.


Main Effects and Features


Representative cytokines (growth factors) and their main effects

Cytokines (growth factors) play an important role in restoring the functions of damaged tissues and cells, and are said to be effective in regenerating cells and skin weakened by aging, as well as improving various diseases. It is also known that the amount of growth factors produced in the body decreases with age.


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Expected effects of cytokines

EGF (Epidermal Growth Factors)
Improves skin problems such as blemishes, dullness, and wrinkles by promoting cell turnover.

Fibroblast growth factors (FGFs)
It promotes the proliferation of fibroblasts that secrete collagen, thereby repairing tissue.

IGF-1 (Insulin-like Growth Factor-1)
Forms new skin cells and reduces wrinkles.

Promotes angiogenesis, improving the supply of oxygen and nutrients to tissues, and accelerating wound healing.


Our product features and lineup

No Animal Origins


Antibiotic -free

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Product lineup

product name
Product No
Stem S
Stem S
Japanese (fat)
Japanese (fat)
1mL/10 bottles
1mL/5 bottles


Choose your exosomes

Another option for patients.
The cytokine content is maintained at a very high level while being exosome-free.
We can provide more personalized treatment based on the characteristics of each patient.


High concentration and high quality

It showed an overwhelmingly high cytokine content compared to other supernatants.
This is a high-quality supernatant produced from fresh stem cells in the culture and processing facility attached to the clinic.
​Manufactured with permission from the Ministry of Health, Labor and Welfare, under the supervision of a doctor and in compliance with GMP standards.


Completely made in Japan

The donor was selected according to strict criteria, and the adipose-derived stem cell culture supernatant was collected from a healthy Japanese female donor in her 20s.
The origin and safety are clear.


Passed rigorous safety tests

Donors are tested for infectious diseases and viruses, and the collected fat tissue is tested for sterility according to strict standards.
We maintain a high level of safety by conducting sterility tests, virus tests, human irritation and sensitization tests, and harmful substance tests on stem cell culture supernatant.

Doctor's cosmetics

A beauty essence containing stem cell supernatant from the Life Science Institute

Thanks to an innovative technology that allows beauty ingredients to penetrate deep into the stratum corneum *1, it is now possible to reach areas that previously could only be reached using needles or iontophoresis.

The beauty ingredients penetrate deep into the stratum corneum, providing moisturizing and anti-aging care with a beauty serum containing supernatant liquid.

With unprecedented penetration power, you can achieve the skin you desire, with moisture and firmness.

* Human stem cell culture medium "M-CEL®" jointly developed by Hosokawa Micron Corporation and M Regeneration Clinic

It is formulated as a freeze-dried powder containing a permeable, sustained-release "PLGA capsule" encapsulating


Inquiries and orders for supernatant liquid
Please feel free to contact us.

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